Milí kolegové a kolegyně,
chtěli bychom vás srdečně pozvat na další přednášku semináře, která se koná tuto středu 6.12.2017, od 17:20 v posluchárně S4.
Hostem na semináři bude Audrey Lin z University of Oxford, UK, a téma přednášky bude
Rates of evolutionary change in ancient domesticated animals
Těšíme se srdečně na vaši účast!
Za všechny organizátory semináře s pozdravem, Petr Daněček
Stránky semináře http://bioinformatika.mff.cuni.cz/seminar/
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Speaker: Audrey Lin
Title: Rates of evolutionary change in ancient domesticated animals
Abstract: The molecular clock hypothesis is described as the accumulation of nucleotide substitutions at a constant rate over time. This rate can then be used to estimate divergence times between sequences. However, in reality, molecular clocks do not “tick” consistently over time and instead, there is a measurable continuous transition from an increased, short-term mutation rate to a slow, long- term substitution rate.
The hypothesis of time-dependency in molecular evolution states that the rate of observable evolution varies depending on the timeframe over which the rate is measured. To test this hypothesis, I use high-quality mitochondrial genomes of direct-dated domesticated and wild animals.
This study may yield interesting observations on the evolutionary dynamics regarding the genetic processes of domestication within and between the different animal populations of study, as well as improve fossil calibration of current molecular clock models.