Dear all,
the next seminar will take place on Wednesday, please see the
details below. We look forward to seeing you all!
Title: Computational methods for prosthetic vision: inferring
functional structure of the brain from its spontaneous activity
Speaker: Karolína Korvasová (Charles University, Faculty of
Mathematics and Physics)
Date and time: Wednesday 10/04/2024 - 17:20
Location: MFF UK, Malostranské nám. 25, lecture hall S4
https://bioinformatics.cuni.cz/seminar/
Best wishes,
Petr Danecek
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Karolína Korvasová (Charles University, Faculty of
Mathematics and Physics)
Computational methods for prosthetic vision: inferring
functional structure of the brain from its spontaneous
activity
Being able to infer the functional structure
of cortical neural networks from their spontaneous activity would
advance our understanding of neural dynamics and have important
applications in the field of visual prosthetics, as functional
properties of neurons in the visual cortex cannot be measured
directly in blind subjects. We designed a method that estimates
the structure of the orientation preference map in the primary
visual cortex. Using this method, we were able to show that
functional, as well as spatial properties of the sites stimulated
with a cortical visual prosthesis in blind humans determine the
perceptual outcome. In this talk I will first introduce some basic
concepts of computational neuroscience and discuss how biological
neural networks can be modeled. Next, I will briefly present a
large-scale model of the primary visual cortex developed in the
group of Ján Antolík (MFF UK) that was used to design the method
that infers functional structure from spontaneous activity.
Finally, I will show the results of this method applied to
electrophysiological recordings from the visual cortex of sighted
non-human primates and blind human volunteers.