Please join us for our Bioinformatics Seminar tomorrow at 17:20 on Wednesday 24th November 2021
Title:
MTPpilot: an interactive software for NGS results analysis
for molecular tumor boards
Speaker:
Abdullah Kahraman
Abstract: Next-Generation Sequencing (NGS) cancer panels have
become a key cornerstone for today’s clinical decision making in
oncology. In this context, NGS sequencing results are often
discussed at molecular tumor boards, where amongst other
oncologists, pathologists, bioinformaticians, and geneticists
discuss these results to decide on the best treatment options
for a patient. However, with the increasing size and complexity
of NGS cancer panels, NGS results have become challenging to
interpret, especially if presented merely in the form of a
written report. Manual analysis of several mutations from a
comprehensive NGS cancer panel is time-consuming and often
incomplete. To address these shortcomings, I will present our
Molecular Tumor Profiling Pilot (MTPpilot) software, which
provides automated annotation, linking and interactive
visualization to support the interpretation of NGS results at
molecular tumor boards.