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bioinf-l@kam.mff.cuni.cz

October 2022

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Lecture invitation: Measures of quality of clusters in hierarchical clustering of flow cytometry data
by Petr Danecek 14 Oct '22

14 Oct '22

Dear all, the next seminar will take place next week, please see the details below. We look forward to seeing you all! Title: Measures of quality of clusters in hierarchical clustering of flow cytometry data Speaker: Tomáš Sieger Date and time: Wednesday 19/10/2022 - 17:20 Location: MFF UK, Malostranské nám. 25, lecture hall S6 https://bioinformatika.mff.cuni.cz/seminar/ Best wishes, Petr Danecek ---------------- *Tomáš Sieger: **/Measures of quality of clusters in hierarchical clustering of flow cytometry data/* Hierarchical clustering enables unsupervised analysis of multidimensional data, yielding a dendrogram, a hierarchical tree of clusters of data samples. However, the dendrogram does not readily specify the quality of individual clusters in it. In the lecture, we will show measures of quality of clusters in hierarchical clustering, developed in our group, that can be used to guide selection of meaningful clusters in flow cytometry data. The new unsupervised method enables automated processing of large amounts of data without a need of costly and subjective manual intervention. In future, we need to study the general applicability of our measures of cluster quality and validate them on other data sets.

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